Saketh Guntupalli, MD

Specialty: Gynecologic Oncology

Clinical Locations

UCHealth CU Cancer Center
Anschutz Medical Campus

1665 Aurora Court
Aurora, CO 80045

UCHealth Highlands Ranch Hospital Cancer Center
1500 Park Central Drive
Highlands Ranch, CO 80129

St. Mary's Medical Center
CU Cancer Center

2635 N. 7th Street
Grand Junction, CO 81501

Regional West Physicians Clinic - Women's Center
Medical Plaza South
3911 Avenue B, Suite 3100
Scottsbluff, NE 69361

Request Appointment:

(303) 724-2066 | Request Appointment Online


Procedures & specialties

  • Gynecologic Oncology
  • Gynecology & Complex Pelvic Surgery
  • Minimally Invasive & Robotic Surgery
  • Fertility-Sparing Surgeries

About Dr. Guntupalli

Saketh R. Guntupalli, MD is Professor and Director of the Division of Gynecologic Oncology at the University of Colorado School of Medicine at Denver. In this role he leads one of the largest groups of physicians dedicated to women's cancer in the United States. He holds the Karen M. Jennison Endowed Chair in Gynecologic Oncology and also serves as Vice-Chair for Faculty Affairs and Development in the Department of OB-GYN. He received his undergraduate degree from the Johns Hopkins University and his medical degree from the University of Texas at Houston. After a 4-year residency in obstetrics and gynecology at Baylor College of Medicine in Houston, Dr. Guntupalli completed an additional 3-year surgical fellowship in gynecologic oncology and advanced pelvic surgery at Washington University in St. Louis.

Dr. Guntupalli is a leading national and international expert in women's cancer and has lectured all over the world on surgical expertise and molecular mechanisms of cancer. He has authored over 90 clinical papers and has led multiple collaborative research studies focused on improving post-operative surgical outcomes as well as identifying novel therapies for the treatment of ovarian and uterine cancer. With over $5,000,000 in independent research funding, Dr. Guntupalli has led the NRG collaborative research consortium at the University of Colorado Cancer Center for nearly 4 years. Dr. Guntupalli has as an additional expertise in sexual dysfunction broadly in cancer patients, and has authored a New York Times reviewed book and multiple editorials in Forbes. He serves on multiple national committees including the Chair of Legislative Affairs for the Society of Gynecologic Oncology and as well as serving on the executive committee of the Western Association of Gynecologic Oncologists. He is a member of the editorial board of Obstetrics and Gynecology.

Video: Dr. Guntupalli explains why he wrote the book Sex & Cancer

Education

View and download full CV
  • MD, University of Texas Medical School at Houston (2005)
  • BA, Johns Hopkins University (MD) (2001)

Post Graduate Medical Education

  • Residency Program, Baylor College of Medicine Program, Obstetrics and Gynecology (2009)
  • Fellowship, Washington University/Barnes-Jewish Hospital/St. Louis Children’s Hospital, Obstetrics and Gynecology - Gynecologic Oncology (2012)

Board Certification & Licensure

  • American Board of Obstetrics and Gynecology Certified in Obstetrics & Gynecology, Gynecologic Oncology
  • Colorado State Medical License Active through 2021

Language Fluency

  • Spanish, German, French, Hindi and Telugu

Work Experience

  • Associate Professor, Obstetrics and Gynecology, University of Colorado School of Medicine
  • Karen M. Jennison Endowed Chair in Gynecologic Oncology
  • Chief, Division of Gynecologic Oncology
  • Director, Placenta Accreta Response Team (P.A.R.T.)
  • Vice-Chair for Clinical Affairs and Quality, 2016-2019
  • Fellowship Program Director, 2016-2019, Division of Gynecology Oncology, University Colorado School of Medicine
  • Assistant Residency Program Director, 2012

Publications

  • Moroney M Davies JD Wilberger AC Sheeder J Post MD Berning AA Fisher C Lefkowits CL Guntupalli SR Behbakht K Corr BR Molecular markers in recurrent stage I, grade 1 endometrioid endometrial cancers Gynecol Oncol 2019 Jun: 153(3) 517-520
  • Urban RR, Ramzan AA, Doo DW, Sheeder J, Guntupalli SR The perceptions of gynecologic oncology fellows on readiness for subspeciality training following OB/GYN residency Gynecol Oncol Rep 2019 Mar 20: 28; 141-143 PMID 30997375
  • Goodfellow PJ Books R Trichlet D Darcy K Guntupalli SR et al GOG 8020/210: Risk Stratification of Lymph Node Metastasis, Disease Progression and Survival Using Single Nucleotide Polymorphisms in Endometrial Cancer: an NRG Oncology/Gynecologic Oncology Group study Gynecol Oncol 2019 Feb 090-8258 (19) 3-138-6 PMID 30827726
  • Guntupalli SR What’s New in Venous Thromboembolism Prevention in Gynecologic Surgery Obstet and Gynecol 2019 Feb 4 PMID 30741818
  • Matsuo K, Machida H, Horowitz MP, Shahzad MMK, Guntupalli SR, Roman LD, Wright JD. Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer. Am J Obstet Gynecol. 2017 Nov;217(5)
  • Rose PG Java JJ Salani R Gellar MA Guntupalli SR et al Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma. Obstet Gynecol. 2019 Feb;133(2):245-254. PMID 30633128
  • Whitmore G Ramzan AA Sheeder J Guntupalli SR African-American Race is a Predictor of Neoadjuvant Chemotherapy Use Over Primary Debulking Surgery in Women with Advanced Stage Ovarian Cancer Accepted for publication: Journal of the National Medical Association
  • Felix AF Brasky T Bogess J Guntupalli SR et al Receipt of adjuvant endometrial cancer treatment according to race: An NRG Oncology/Gynecologic Oncology Group 210 Study Am J of Obset Gynecol. 2018 Nov;219(5):e1-458.e11 PMID 30096321
  • Ramzan AA Behbakht K Corr BR Sheeder J Guntupalli SR Minority race and ethnicity is a significant risk factor for treatment by non-gynecologic oncologists in women with gynecologic malignancy Ann Surg Oncology 2018 Nov;25(12):3685-3691 PMID 30105439
  • Moroney MR Flink DM Sheeder J Blake E Carrubba AR Fisher CF Guntupalli SR Radiation therapy is not an independent risk factor for sexual dysfunction in women with gynecologic cancers Rep Pract Oncol Radiother 2018 Sep-Oct;23(5):331-336 PMID 30127672
  • Urban RR, Ramzan AA, Doo DW, Galan HL, Harper L, Omurtag K, Muffly TM, Sheeder J, Guntupalli SR. Fellow perceptions of residency training in obstetrics and gynecology Am J Obstet Gynecol 218(4); 420-422 2018 PMID 29353035
  • Wheeler L, Guntupalli SR. Germline testing for predisposition to ovarian/breast cancer should be routinely recommended in all patients with invasive epithelial ovarian cancer. Ind J Gynecol Oncol 2017 15 (Suppl 1):27
  • Felix AS, Brasky, TM, Cohn, DE, Mutch, DG, Guntupalli SR, Downs, LS, et al. Endometrial carcinoma recurrence according to race and ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study Int J of Cancer 142(6):1102-1115 2018 PMID: 29063589
  • Matsuo K, Machida H, Horowitz MP, Shahzad MMK, Guntupalli SR, Roman LD, et al. Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer. Am J Obstet Gyneco 217(5):580.e1-580/e10 2017 PMID: 28666700
  • Reyes HD, Miecznikowski J, Gonzalez-Bosquet J, Devor EJ, Zhang Y, Guntupalli SR, et al. High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study. Gynecol Oncol 146(2):247-253 2017 PMID: 28532857
  • Brasky TM, Felix AS, Cohn DE, McMeekin DS, Mutch DG, Guntupalli SR, et al. Nonsteroidal Anti-inflammatory Drugs and Endometrial Carcinoma Mortality and Recurrence. J Natl Cancer Inst. 1;109(3):1-10 2017 PMID: 28376204
  • Blake EA, Sheeder J, Carrubba A, Okland T, Doo D, Guntupalli SR Risk Factors for Clostridium Difficile Colitis in Patients Undergoing Treatment for Gynecologic Cancer. Clin Oncol. 2: 1190 2017.
  • Blake EA, Flink DM, Sheeder J, Carrubba A, Maroney M, Guntupalli SR Chemotherapy Use Is a Significant Predictor for Sexual Dysfunction in Women with Gynecologic Cancer. Journal of Cancer Therapy, 8, 321-326 2017.
  • Creasman WT, Ali S, Mutch DG, Zaino RJ, Powell MA, Guntupalli SR, et al. Surgical-pathological findings in type 1 and 2 endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study on GOG-210 protocol. Gynecol Oncol. 145(3):519-535. PMID: 28392124
  • Corr BR, Carrubba A, Sheeder J, Cheng G, Guntupalli SR. Histopathology Discrepancy of Preoperative Endometrial Sampling and Final Specimen: How Does This Influence Selective Lymph Node Dissection? Int J Gynecol Cancer 27(2):297-301 PMID: 27870710
  • Carrubba AM, Flink DM, Sheeder JA, Moroney M, Guntupalli SR Surgical management is associated with sexual dysfunction in gynecologic cancer Cogent Medicine Vol. 3, Iss.1 2016
  • Guntupalli SR, Ioffe Y, Sheeder JS, Tergas A, Wright JD, Behbakht K, et al. Sexual and Marital Dysfunction in Women with Gynecologic Cancer Int J of Gynecol Cancer. 3/2017 PMID: 28129243
  • Backes CH, Bonachea EM, Rivera BK, Reynolds MM, Kovalchin CE, Guntupalli SR, et al. Preparedness of pediatric residents for fellowship: a survey of US neonatal-perinatal fellowship program directors. J Perinatol. 36(12):1132-1137 2016 PMID: 27287506
  • Carlson M, Guntupalli SR, Koh E Wright JD. SGO Health Policy and Socioeconomic Committee: Current and future efforts of the Future of Physician Payment Reform Taskforce and the Legislative and Regulatory Affairs Taskforce. Gynecol Oncol 142(3):385-387 2016 PMID: 27287506
  • Amini A, Yeh N, Rusthoven C, Guntupalli SR, Karam S, Fisher C. Perioperative Mortality in Nonelderly Adult Patients with Cancer: A Population-Based Study Evaluating Healthcare Disparities in the United States According to Insurance Status Am J of Clin Oncol 2016 Jun 6 PMID: 27281264
  • Amini A, Jones BL, Yeh N, Guntupalli SR, Kavanagh BD, Karam SD, et al. Disparities in disease presentation in the four screenable cancers according to health insurance status. Public Health. 138:50-6 2016 PMID: 27091437
  • Blake EA, Sheeder J, Behbakht K, Guntupalli SR, Guy MS. Factors Impacting Use of Robotic Surgery for Treatment of Endometrial Cancer in the United States. Ann Surg Oncol. 23(11) 3744-3748 2016 PMID: 27172774
  • Guntupalli SR Preparedness of Obstetrics and Gynecology Residents for Fellowship Training; The Sky Is Not Falling, But It Is Severely Drooping for the Specialist Obstetrician-Gynecologist; Response to Letter to Editor; Obstet Gynecol 127(1): 161 2016 PMID: 26695564
  • Carruba AM, Sheeder J, Corr BR, Guntupalli SR. Evaluation of Preoperative Chest Imaging in Low-Risk Endometrial Cancer Patients Int J Gynecol Cancer 26(2):348-53 2016 PMID: 26807565
  • Doo DW, Guy MS, Behbakht K, Davidson SA, Sheeder J, Guntupalli SR Association Between Preoperative Chemotherapy and Postoperative Complications in Patients Undergoing Surgery for Ovarian Cancer: Results from a National Inpatient Review Ann Surg Onc 23 93 0:968-974 2016 PMID: 26542594
  • Guntupalli SR, Doo DW, Guy M, Sheeder J, Omurtag K, Kondapalli L, Valea F, Harper L, Muffly TM. “Preparedness of Obstetrics and Gynecology Residents for Fellowship Training.” Obstetrics & Gynecology. September 2015;126(3):559-68.
  • Guy MS Sheeder JA Davidson S Behbakht K Wright JA Guntupalli SR Comparative outcomes in older and younger women undergoing laparotomy or robotic surgical staging for endometrial cancer. Accepted for publication in American Journal of Obstetrics and Gynecology. June 2015
  • Doo D, Guy MS, Sheeder J, Powell MA, Novetsky AP, Guntupalli SR Preparedness of OB-GYN Residents for Fellowship Training in Gynecologic Oncology: Results of National Survey Accepted for publication in Gynecologic Oncology. Sept. 2015
  • Lamale-Smith LM, Moore GS, Guntupalli SR, Scott JB. Maternal-Fetal Transfer of Anti-N-Methyl-D-Aspartate Receptor Antibodies. Obstetrics & Gynecology. 2015 Feb 11 PMID: 25710615
  • Doo D, Guy MS, Sheeder JA, Behbakht K Guntupalli SR Comparative outcomes of robotic surgery versus laparotomy in elderly patients with gynecologic cancer. Ann Surg Oncol. 2015 (1): 1921-1928 PMID: 25672563
  • Blake E, Cheng G, Post M, Guntupalli SR Cotyledonoid Dissecting Leiomyoma: A Case Report and Review of Literature Accepted for publication in Gynecologic Oncology Case Reports. (Nov. 2014)
  • Anderson CA, Medlin E, Ferris-Fontenot A, Behbakht K, Davidson S, Gibbs RA, Sheeder JA, Guntupalli SR Association of Gel-Thrombin matrix use and abscesses in women undergoing pelvic surgery. Obstetrics & Gynecology. Sept. 2014;124(3):589-95 PMID: 25162261
  • Novetsky AP, Ioffe YJ, Kizer NK, Guntupalli SR, Powell MA, Mutch DG, Thaker PH, Hagemann AT, Massad LS A phase II trial of a surgical protocol to decrease the incidence of wound complications in obese gynecologic oncology patients. Gynecol Oncol. Aug. 2014;134(2):233-7 PMID: 24952366
  • Hopkins M, Richmond A, Cheng G, Sheeder J, Post M Davidson S, Spillman M, Guntupalli SR Lymphovascular Space Invasion in Robotic Surgery for Uterine Cancer JSLS. July 18, 2014; 3 PMID: 25392608
  • Lee JL Guntupalli SR Diamond J Theodorescu D Behbakht K Kim YC Retrospective analysis of survival improvement by molecular biomarker-based personalized chemotherapy for recurrent ovarian cancer. PLOS One. 2014 9(2):86532 PMID: 24505259
  • Guy MS, Cheng G, Sheeder J, Post M, Behbakht K, Davidson S, Spillman M, Guntupalli SR Outcomes of women with atypical glandular cells on pre-operative cervical cytology and endometrial cancer. International Journal of Gynecologicc Cancer. 2014 24(2):266-71 PMID: 24401985
  • Guntupalli SR, Cao D, Shroff R, Gao F, Menias C, Stewart Massad L, Powell MA, Mutch DG, Thaker PH. Wilms' Tumor 1 Protein and Estrogen Receptor Beta Expression are Associated with Poor Outcomes in Uterine Carcinosarcoma. Ann Surg Oncol. 2013 Jan 24 PMID:23344579
  • Tergas AI, Havrilesky LJ, Fader A, Guntupalli SR, Huh WK, Massad LS, Rimel BJ Cost Analysis of Colposcopy for Abnormal Cytology in Post-treatment Surveillance for Cervical Cancer. Gynecologic Oncology. 2013 PMID:23747836
  • Guntupalli SR, Zighelboim I, Kizer NT, Powell MA, Thaker PH, Goodfellow PJ, Mutch DG Lymphovascular Space Invasion Predicts Nodal Disease and Poor Outcomes in Patients with Endometrial Cancer. Gynecologic Oncology. 2012 Jan; 124(1):31-5. PMID: 22030404
  • Kizer NT, Gao F, Guntupalli SR, Thaker PH, Powell MA, Goodfellow PJ, Mutch DG, Zighelboim I. Lower Uterine Segment Involvement is Associated with Poor Outcomes in Early-Stage Endometrioid Endometrial Carcinoma. Ann Surg Oncol. 2012 18(5):1419-24. PMID: 21181281
  • Squires KE, Guntupalli SR, Thaker PH Eptifibatide Induced Profound Thrombocytopenia in a Patient with Pelvic Malignancy: A Case Report. Gynecologic Oncology. 2012 Aug; 75-77
  • Guntupalli SR, Mutch DG Abnormal Cervical Cytology Glass’ Office Gynecology –Eight Edition Lippincott Williams, New York, NY 2010
  • Guntupalli SR, Ramirez PT, Anderson ML, Milam MR, Bodurka DC, Malpica A. Uterine smooth muscle tumor of uncertain malignant potential: a retrospective analysis. Gynecologic Oncology. 2009 113(3):324-6. PMID: 19342083
  • Guntupalli SR, Anderson ML, Bodurka DC.Alveolar soft part sarcoma of the cervix: case report and literature review. Arch Gynecol Obstet. 2009 279(2):263-5. PMID: 18548261
  • Guntupalli SR, Steingrub J Hepatic disease and pregnancy: An overview of diagnosis and management. Critical Care Medicine. 2005 Oct 33; (10 suppl): 332-9. PMID: 16215356

Awards & Recognitions

  • 2015 Vitals Patients' Choice Award winner
  • Top Doc (2014)
  • Health Grades Honor Roll
  • Baylor College of Medicine, Resident of the Year, Department of Obstetrics and Gynecology (2009)

Did you know?

In his spare time, Dr. Guntupalli is a close follower of national politics, hiker and basketball fan.