Saketh R. Guntupalli, MD is Associate Professor, Karen M. Jennison Endowed Chair in Gynecologic Oncology, and Director of the Division of Gynecologic Oncology at the University of Colorado School of Medicine at Denver. He formerly served as Vice-Chair for Clinical Affairs/Quality in the Department of OB-GYN and director of the fellowship program in gynecologic oncology. He received his undergraduate degree from the Johns Hopkins University and his medical degree from the University of Texas at Houston. After a 4-year residency in obstetrics and gynecology at Baylor College of Medicine, Dr. Guntupalli completed an additional 3-year surgical fellowship in gynecologic oncology and advanced pelvic surgery at Washington University in St. Louis.
Dr. Guntupalli is a leading national and international expert in women’s cancer and has lectured all over the world on surgical expertise and molecular mechanisms of cancer. He has authored over 60 clinical papers and has led multiple collaborative research studies focused on improving post-operative surgical outcomes as well as identifying novel therapies for the treatment of ovarian and uterine cancer. With over $3,000,000 in independent research funding, Dr. Guntupalli has led the NRG collaborative research consortium at the University of Colorado Cancer Center for nearly 4 years. Dr. Guntupalli has as an additional expertise in sexual dysfunction broadly in cancer patients, and has authored a New York Times reviewed book and multiple editorials in Forbes. He serves on multiple national committees including the Chair of Legislative Affairs for the Society of Gynecologic Oncology and as well as serving on the executive committee of the Western Association of Gynecologic Oncologists. He is a member of the editorial board of Obstetrics and Gynecology.
In his spare time, Dr. Guntupalli is a close follower of national politics, hiker and basketball fan.
MD, University of Texas Medical School at Houston (2005)
BA, Johns Hopkins University (MD) (2001)
Post Graduate Medical Education
Residency Program, Baylor College of Medicine Program, Obstetrics and Gynecology (2009)
Fellowship, Washington University/Barnes-Jewish Hospital/St. Louis Children’s Hospital, Obstetrics and Gynecology - Gynecologic Oncology (2012)
Board Certification & Licensure
American Board of Obstetrics and Gynecology Certified in Obstetrics & Gynecology, Gynecologic Oncology
Colorado State Medical License Active through 2021
Language Fluency
Spanish, German, French, Hindi and Telugu
Work Experience
Associate Professor, Obstetrics and Gynecology, University of Colorado School of Medicine
Karen M. Jennison Endowed Chair in Gynecologic Oncology
Chief, Division of Gynecologic Oncology
Director, Placenta Accreta Response Team (P.A.R.T.)
Vice-Chair for Clinical Affairs and Quality, 2016-2019
Fellowship Program Director, 2016-2019, Division of Gynecology Oncology, University Colorado School of Medicine
Assistant Residency Program Director, 2012
Publications
Moroney M Davies JD Wilberger AC Sheeder J Post MD Berning AA Fisher C Lefkowits CL Guntupalli SR Behbakht K Corr BR Molecular markers in recurrent stage I, grade 1 endometrioid endometrial cancers Gynecol Oncol 2019 Jun: 153(3) 517-520
Urban RR, Ramzan AA, Doo DW, Sheeder J, Guntupalli SR The perceptions of gynecologic oncology fellows on readiness for subspeciality training following OB/GYN residency Gynecol Oncol Rep 2019 Mar 20: 28; 141-143 PMID 30997375
Goodfellow PJ Books R Trichlet D Darcy K Guntupalli SR et al GOG 8020/210: Risk Stratification of Lymph Node Metastasis, Disease Progression and Survival Using Single Nucleotide Polymorphisms in Endometrial Cancer: an NRG Oncology/Gynecologic Oncology Group study Gynecol Oncol 2019 Feb 090-8258 (19) 3-138-6 PMID 30827726
Guntupalli SR What’s New in Venous Thromboembolism Prevention in Gynecologic Surgery Obstet and Gynecol 2019 Feb 4 PMID 30741818
Matsuo K, Machida H, Horowitz MP, Shahzad MMK, Guntupalli SR, Roman LD, Wright JD. Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer. Am J Obstet Gynecol. 2017 Nov;217(5)
Rose PG Java JJ Salani R Gellar MA Guntupalli SR et al Nomogram for Predicting Individual Survival After Recurrence of Advanced-Stage, High-Grade Ovarian Carcinoma. Obstet Gynecol. 2019 Feb;133(2):245-254. PMID 30633128
Whitmore G Ramzan AA Sheeder J Guntupalli SR African-American Race is a Predictor of Neoadjuvant Chemotherapy Use Over Primary Debulking Surgery in Women with Advanced Stage Ovarian Cancer Accepted for publication: Journal of the National Medical Association
Felix AF Brasky T Bogess J Guntupalli SR et al Receipt of adjuvant endometrial cancer treatment according to race: An NRG Oncology/Gynecologic Oncology Group 210 Study Am J of Obset Gynecol. 2018 Nov;219(5):e1-458.e11 PMID 30096321
Ramzan AA Behbakht K Corr BR Sheeder J Guntupalli SR Minority race and ethnicity is a significant risk factor for treatment by non-gynecologic oncologists in women with gynecologic malignancy Ann Surg Oncology 2018 Nov;25(12):3685-3691 PMID 30105439
Moroney MR Flink DM Sheeder J Blake E Carrubba AR Fisher CF Guntupalli SR Radiation therapy is not an independent risk factor for sexual dysfunction in women with gynecologic cancers Rep Pract Oncol Radiother 2018 Sep-Oct;23(5):331-336 PMID 30127672
Urban RR, Ramzan AA, Doo DW, Galan HL, Harper L, Omurtag K, Muffly TM, Sheeder J, Guntupalli SR. Fellow perceptions of residency training in obstetrics and gynecology Am J Obstet Gynecol 218(4); 420-422 2018 PMID 29353035
Wheeler L, Guntupalli SR. Germline testing for predisposition to ovarian/breast cancer should be routinely recommended in all patients with invasive epithelial ovarian cancer. Ind J Gynecol Oncol 2017 15 (Suppl 1):27
Felix AS, Brasky, TM, Cohn, DE, Mutch, DG, Guntupalli SR, Downs, LS, et al. Endometrial carcinoma recurrence according to race and ethnicity: An NRG Oncology/Gynecologic Oncology Group 210 Study Int J of Cancer 142(6):1102-1115 2018 PMID: 29063589
Matsuo K, Machida H, Horowitz MP, Shahzad MMK, Guntupalli SR, Roman LD, et al. Risk of metachronous ovarian cancer after ovarian conservation in young women with stage I cervical cancer. Am J Obstet Gyneco 217(5):580.e1-580/e10 2017 PMID: 28666700
Reyes HD, Miecznikowski J, Gonzalez-Bosquet J, Devor EJ, Zhang Y, Guntupalli SR, et al. High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study. Gynecol Oncol 146(2):247-253 2017 PMID: 28532857
Brasky TM, Felix AS, Cohn DE, McMeekin DS, Mutch DG, Guntupalli SR, et al. Nonsteroidal Anti-inflammatory Drugs and Endometrial Carcinoma Mortality and Recurrence. J Natl Cancer Inst. 1;109(3):1-10 2017 PMID: 28376204
Blake EA, Sheeder J, Carrubba A, Okland T, Doo D, Guntupalli SR Risk Factors for Clostridium Difficile Colitis in Patients Undergoing Treatment for Gynecologic Cancer. Clin Oncol. 2: 1190 2017.
Blake EA, Flink DM, Sheeder J, Carrubba A, Maroney M, Guntupalli SR Chemotherapy Use Is a Significant Predictor for Sexual Dysfunction in Women with Gynecologic Cancer. Journal of Cancer Therapy, 8, 321-326 2017.
Creasman WT, Ali S, Mutch DG, Zaino RJ, Powell MA, Guntupalli SR, et al. Surgical-pathological findings in type 1 and 2 endometrial cancer: An NRG Oncology/Gynecologic Oncology Group study on GOG-210 protocol. Gynecol Oncol. 145(3):519-535. PMID: 28392124
Corr BR, Carrubba A, Sheeder J, Cheng G, Guntupalli SR. Histopathology Discrepancy of Preoperative Endometrial Sampling and Final Specimen: How Does This Influence Selective Lymph Node Dissection? Int J Gynecol Cancer 27(2):297-301 PMID: 27870710
Carrubba AM, Flink DM, Sheeder JA, Moroney M, Guntupalli SR Surgical management is associated with sexual dysfunction in gynecologic cancer Cogent Medicine Vol. 3, Iss.1 2016
Guntupalli SR, Ioffe Y, Sheeder JS, Tergas A, Wright JD, Behbakht K, et al. Sexual and Marital Dysfunction in Women with Gynecologic Cancer Int J of Gynecol Cancer. 3/2017 PMID: 28129243
Backes CH, Bonachea EM, Rivera BK, Reynolds MM, Kovalchin CE, Guntupalli SR, et al. Preparedness of pediatric residents for fellowship: a survey of US neonatal-perinatal fellowship program directors. J Perinatol. 36(12):1132-1137 2016 PMID: 27287506
Carlson M, Guntupalli SR, Koh E Wright JD. SGO Health Policy and Socioeconomic Committee: Current and future efforts of the Future of Physician Payment Reform Taskforce and the Legislative and Regulatory Affairs Taskforce. Gynecol Oncol 142(3):385-387 2016 PMID: 27287506
Amini A, Yeh N, Rusthoven C, Guntupalli SR, Karam S, Fisher C. Perioperative Mortality in Nonelderly Adult Patients with Cancer: A Population-Based Study Evaluating Healthcare Disparities in the United States According to Insurance Status Am J of Clin Oncol 2016 Jun 6 PMID: 27281264
Amini A, Jones BL, Yeh N, Guntupalli SR, Kavanagh BD, Karam SD, et al. Disparities in disease presentation in the four screenable cancers according to health insurance status. Public Health. 138:50-6 2016 PMID: 27091437
Blake EA, Sheeder J, Behbakht K, Guntupalli SR, Guy MS. Factors Impacting Use of Robotic Surgery for Treatment of Endometrial Cancer in the United States. Ann Surg Oncol. 23(11) 3744-3748 2016 PMID: 27172774
Guntupalli SR Preparedness of Obstetrics and Gynecology Residents for Fellowship Training; The Sky Is Not Falling, But It Is Severely Drooping for the Specialist Obstetrician-Gynecologist; Response to Letter to Editor; Obstet Gynecol 127(1): 161 2016 PMID: 26695564
Carruba AM, Sheeder J, Corr BR, Guntupalli SR. Evaluation of Preoperative Chest Imaging in Low-Risk Endometrial Cancer Patients Int J Gynecol Cancer 26(2):348-53 2016 PMID: 26807565
Doo DW, Guy MS, Behbakht K, Davidson SA, Sheeder J, Guntupalli SR Association Between Preoperative Chemotherapy and Postoperative Complications in Patients Undergoing Surgery for Ovarian Cancer: Results from a National Inpatient Review Ann Surg Onc 23 93 0:968-974 2016 PMID: 26542594
Guntupalli SR, Doo DW, Guy M, Sheeder J, Omurtag K, Kondapalli L, Valea F, Harper L, Muffly TM. “Preparedness of Obstetrics and Gynecology Residents for Fellowship Training.” Obstetrics & Gynecology. September 2015;126(3):559-68.
Guy MS Sheeder JA Davidson S Behbakht K Wright JA Guntupalli SR Comparative outcomes in older and younger women undergoing laparotomy or robotic surgical staging for endometrial cancer. Accepted for publication in American Journal of Obstetrics and Gynecology. June 2015
Doo D, Guy MS, Sheeder J, Powell MA, Novetsky AP, Guntupalli SR Preparedness of OB-GYN Residents for Fellowship Training in Gynecologic Oncology: Results of National Survey Accepted for publication in Gynecologic Oncology. Sept. 2015
Doo D, Guy MS, Sheeder JA, Behbakht K Guntupalli SR Comparative outcomes of robotic surgery versus laparotomy in elderly patients with gynecologic cancer. Ann Surg Oncol. 2015 (1): 1921-1928 PMID: 25672563
Blake E, Cheng G, Post M, Guntupalli SR Cotyledonoid Dissecting Leiomyoma: A Case Report and Review of Literature Accepted for publication in Gynecologic Oncology Case Reports. (Nov. 2014)
Anderson CA, Medlin E, Ferris-Fontenot A, Behbakht K, Davidson S, Gibbs RA, Sheeder JA, Guntupalli SR Association of Gel-Thrombin matrix use and abscesses in women undergoing pelvic surgery. Obstetrics & Gynecology. Sept. 2014;124(3):589-95 PMID: 25162261
Novetsky AP, Ioffe YJ, Kizer NK, Guntupalli SR, Powell MA, Mutch DG, Thaker PH, Hagemann AT, Massad LS A phase II trial of a surgical protocol to decrease the incidence of wound complications in obese gynecologic oncology patients. Gynecol Oncol. Aug. 2014;134(2):233-7 PMID: 24952366
Hopkins M, Richmond A, Cheng G, Sheeder J, Post M Davidson S, Spillman M, Guntupalli SR Lymphovascular Space Invasion in Robotic Surgery for Uterine Cancer JSLS. July 18, 2014; 3 PMID: 25392608
Lee JL Guntupalli SR Diamond J Theodorescu D Behbakht K Kim YC Retrospective analysis of survival improvement by molecular biomarker-based personalized chemotherapy for recurrent ovarian cancer. PLOS One. 2014 9(2):86532 PMID: 24505259
Guy MS, Cheng G, Sheeder J, Post M, Behbakht K, Davidson S, Spillman M, Guntupalli SR Outcomes of women with atypical glandular cells on pre-operative cervical cytology and endometrial cancer. International Journal of Gynecologicc Cancer. 2014 24(2):266-71 PMID: 24401985
Squires KE, Guntupalli SR, Thaker PH Eptifibatide Induced Profound Thrombocytopenia in a Patient with Pelvic Malignancy: A Case Report. Gynecologic Oncology. 2012 Aug; 75-77
Guntupalli SR, Mutch DG Abnormal Cervical Cytology Glass’ Office Gynecology –Eight Edition Lippincott Williams, New York, NY 2010
Guntupalli SR, Steingrub J Hepatic disease and pregnancy: An overview of diagnosis and management. Critical Care Medicine. 2005 Oct 33; (10 suppl): 332-9. PMID: 16215356
Awards & Recognitions
2015 Vitals Patients’ Choice Award winner
Top Doc (2014)
Health Grades Honor Roll
Baylor College of Medicine, Resident of the Year, Department of Obstetrics and Gynecology (2009)
Did you know?
Dr. Guntupalli has authored over 40 clinical papers in journals such as the Journal of the National Cancer Institute, Obstetrics and Gynecology, Gynecologic Oncology, and the International Journal of Gynecologic Oncology. He also serves as director for the Placenta Accreta Response Team (PART) at the University of Colorado Hospital.
